Con - structs for Direct Charac - terization of Promoter Regulatory Regions

Performance Charac - terization and Opti - mization of In - Memo - ry Data Analytics on a Scale - up Server AHSAN

In silico screening of G-Quadruplex Structures in Wilms tumor 1 Gene Promoter

Introduction: X-ray diffraction studies have revealed that guanines in a DNA stands may be arranged in quartet and form a structure called G-quadruplexs. Bioinformatics studies suggested the formation of G-quadruplex structure in human crucial genes, including Wilms tumor 1 (WT1). The aim of this study was to in silico analysis of the guanine-rich sequence in the promoter region of the WT1 gene...

P-204: Evaluation of FMR1 Gene Regulatory Region for The Epigenetic Mark of H3K9 Acetylation in Blood Cells of Patients with Diminished Ovarian Reserve Reffered to Royan Institute

Background: Diminished ovarian reserve (DOR) is a heterogeneous disorder causing infertility, characterized by a decreased number of oocytes and high FSH level, the genetic cause of which is still unknown. The association between FMR1 premutations(50-200 CGG repeats) and the premature ovarian failure( POF) disease has suggested that FMR1 gene acts as a risk factor for POF and recently for DOR p...

A Fast Recursive Algorithm for Constructing Matrices with Prescribed Eigenvalues and Singular Values

The Weyl Horn theorem characterizes a relationship between the eigenvalues and the singular values of an arbitrary matrix Based on that charac terization a fast recursive algorithm is developed to construct numerically a matrix with prescribed eigenvalues and singular values Beside being theoretically interest ing the technique could be employed to create test matrices with desired spectral fea...

Genetic polymorphisms in the promoter region of catalase gene, creates new potential PAX-6 and STAT4 response elements

Catalase (CAT, OMIM: 115500) is an endogenous antioxidant enzyme and genetic variations in the regulatory regions of the CAT gene may alter the CAT enzyme activity and subsequently may alter the risk of oxidative stress related disease. In this study, potential influence(s) of the A-21T (rs7943316) and C-262T (rs1001179) genetic polymorphisms in the CAT promoter region, using the ALGGEN-PROMO.v...